The Association between Vitamin D Level and Chronic Pain and Depression in Premenopausal Women Premenopozal Erişkin Kadinlarda Vitamin D Düzeyi ile Kronik Ağri ve Depresyon Arasindaki İlişki

Objective: To investigate the association between vitamin D level and non-specific musculoskeletal system pain and depression in premenopausal women. Material and Methods: Two hundred eighteen premenopausal women with common musculoskeletal pain and unknown etiology were included into the study. Levels of pain and depression were respectively measured with 0-10 visual analog scale (VAS) and Beck Depression Inventory (BDI). Levels of serum 25(OH)D, parathormone, alkaline phosphatase, and calcium were also measured. The threshold value of vitamin D was accepted as 20 ng/mL. Patients with 25(OH)D 0.05). Whereas a negative correlation was present between level of vitamin D and VAS and BDI scores, no correlation was detected as to age, BMI, level of income, educational status (p 0.05). Conclusion: Our study indicates that vitamin D deficiency is a frequent finding in premenopausal women with chronic, non-specific musculoskeletal pain and that the level of vitamin D is associated with