Predice el Kidney Donor Profile Index (KDPI) la supervivencia del injerto y del paciente en una población española

espanolAntecedentes y objetivo: El Kidney Donor Profile Index (KDPI), junto a otras variables del donante y receptor, puede optimizar el proceso de asignacion de organos. Este estudio tiene como objetivo comprobar la aplicabilidad del KDPI en una poblacion espan˜ ola, asi como su capacidad de prediccion de la supervivencia del injerto y del paciente. Materiales y metodos: Se estudiaron 2.734 trasplantes renales llevados a cabo en Andalucia entre enero de 2006 y diciembre de 2015. Los casos se agruparon por edad del receptor y cuartil del KDPI y se compararon entre grupos tanto la supervivencia del injerto como la del paciente. Resultados: El KDPI discrimina con precision los organos optimos de los suboptimos o marginales. Para receptores entre 18 y 59 anos presenta un hazard ratio de 1,013 (p EnglishBackground and objective: The Kidney Donor Profile Index (KDPI), together with other donor and recipient variables, can optimise the organ allocation process. This study aims to check the feasibility of the KDPI for a Spanish population and its predictive ability of graft and patient survival. Materials and methods: Data from 2,734 kidney transplants carried out in Andalusia between January 2006 and December 2015 were studied. Cases were grouped by recipient age, categorised by KDPI quartile and both graft and patient survival were compared among groups. Results: The KDPI accurately discriminated optimal organs from suboptimal or marginal ones. For adult recipients (aged: 18-59 years) it presents a hazard ratio of 1.013 (P Conclusions: The results obtained show that the KDPI makes it possible to relate the donor’s characteristics with the greater or lesser survival of the graft and the patient in the Spanish population. However, due to certain limitations, a new index for Spain based on Spanish or European data should be created. In this study, some predictive factors of graft survival are identified that may serve as a first step in this path.