Coriaheptocins A and B, the First Heptahydroxylated Acetogenins, Isolated from the Roots of Annona coriacea 1

Two new annonaceous acetogenins, coriaheptocin A (1) and coriaheptocin B (2), have been isolated from the roots of Annona coriacea Mart. (Annonaceae). Heptahydroxylated, they present an unusual 1,3,6,7-tetrol arrangement. Determination of their structures required an original MS and NMR strategy.