Effects of Intrasplenic Injection of Hepatocytes, Hepatocyte Fragments and Hepatocyte Culture Supernatants on D-Galactosamine-Induced Liver Failure in Rats

Dieter Baumgartner,Paulita M. LaPlante-O’Neill,D. E R Sutherland,Najarian Js

Effects of Intrasplenic Injection of Hepatocytes, Hepatocyte Fragments and Hepatocyte Culture Supernatants on D-Galactosamine-Induced Liver Failure in Rats

1983

Dieter Baumgartner
Paulita M. LaPlante-O’Neill
D. E R Sutherland
Najarian Js

Intraperitoneal injection of 0.5 g/kg D -galactosamine results in 95% lethal acute liver failure in male Fisher 344 rats. Intrasplenic injection of viable syngeneic hepatocytes 20–28

Keywords:

Galactosamine
Hepatocyte
Intraperitoneal injection
General surgery
Immunology
Medicine
Cell culture
Endocrinology
liver failure
d galactosamine
liver cell transplantation
Diabetes mellitus
cell culture supernatant
Internal medicine

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