Effect of ligustrazine on canine kidney preservation

The canine kidney autologous transplant model was used to investigate the effect of ligustrazine with a certain concentration added to WMO-1 solution on kidney preservation. The results showed that the canine autologously transplanted kidneys were difficult to survive with 72h preservation of WMO-1 alone and WMO-1 plus ligustrazine. The mean serum creatine level after operation in 48 h ligustrazine preservation group was lower than in 48 h WMO-1 preservation group, and the recovery of serum creatine level in the former group was earlier than in the latter group (P＜0.05). These results suggested that the ligustrazine concentration used could not prolong the preservation time of WMO-1 solution to kidney, but could be of benefit to the recovery of renal function in the early stage. Key words: Key words Tissue preservation Kidney Transplantation; autologous