Simulation of Limb Frostbites in Air Medium

The clinical course of frostbites of the limbs was studied in 3 animal species (swine, dog, rabbit) with frostbites of different intensity and duration. Animals of different species exhibited different sensitivity of their limb tissues to cold. The rabbit proved to be the most adequate animal for frostbite simulation. Frostbites of similar area and depth of lesions can be induced by cooling according to different protocols.