Drug-induced myocardial dysfunction - recommendations for assessment in clinical and pre-clinical studies

Ahmad Ebrahimi,Joel S. Raichlen,Amy Pointon,Christer Gottfridsson,Jiefen Munley,Paul D. Hockings,James Cartwright,Nicholas A Buss,Johannes Wikström,Li-Ming Gan,Andrew Whittaker,Ali Khalil,Richard T George,Pavlo Garkaviy,David Brott

Drug-induced myocardial dysfunction - recommendations for assessment in clinical and pre-clinical studies

2020

Ahmad Ebrahimi
Joel S. Raichlen
Amy Pointon
Christer Gottfridsson
Jiefen Munley
Paul D. Hockings
James Cartwright
Nicholas A Buss
Johannes Wikström
Li-Ming Gan
Andrew Whittaker
Ali Khalil
Richard T George
Pavlo Garkaviy
David Brott

AbstractIntroduction: Drug-induced myocardial dysfunction is an important safety concern during drug development. Oncology compounds can cause myocardial dysfunction, leading to decreased left vent...

Keywords:

Medicine
Diabetes mellitus
Intensive care medicine
Drug
Drug development
Pharmacology

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