Model of spatial structure of human AIMP1/р43 protein

Computer modeling of 3D structure of full-length AIMP1/р43 - component of aminoacyl tRNA synthetase complex in higher eukaryotes, was performed. The model of the spatial structure of the dimer AIMP1/р43 was obtained. Experimental data on the content of the secondary structure of AIMP1/р43 was determined by circular dichroism method. The spatial structure of AIMP1/р43 allows to carry out structural and functional analysis of the interaction with other biologically important molecules