C3A Epithelium Cells Directly Cultured on High-Dielectric Constant Material for Light-Addressable Potentiometric Sensor

To investigate the ion activities of cells based on light-addressable potentiometric sensor (LAPS) platform, various high-dielectric constant sensing membrane were investigated the visibility and potential issue. Three different kinds of well-proven materials in semiconductor industry, such as Si3N4, NbOx, and TiN, are the promising sensing membranes to directly culture C3A cells. TiN and NbOx could be the potential candidate. The photocurrent and flatband voltage difference generated by acidification reaction is verified to observe by LAPS is the future.