SARS-CoV-2 infection associated-meningoencephalitis treated with acyclovir

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus infection is now a pandemic distributed worldwide. All age groups are susceptible to infection, the elderly population, and those with a background of chronic medical comorbidities being particularly vulnerable for severe symptoms and complicated outcome. SARS-CoV-2 infection mainly targets the respiratory system and can establish infection in the upper part of the respiratory tract as well as the lower part of the respiratory tract, presenting in a spectrum ranging from asymptomatic infection reaching up to severe acute respiratory distress syndrome; however, the viral infection is not solely confined to the respiratory system as many cases have been reported where the patients present with different bodily system symptoms without having respiratory symptoms as usual. We report a 51-year old male who presented with symptoms of fever and dry cough and was diagnosed as a case of COVID-19 pneumonia that was later complicated by meningoencephalitis. The patient underwent diagnostic neuroimaging and lumbar puncture; patient received therapy with intravenous acyclovir and intravenous ceftraixone and improved with a favorable outcome. Meningioencephalitis is a serious neurological complication of SARS-CoV-2 infection and should be suspected in patients who develop signs and symptoms suggesting this condition, and we aim from publishing this case to draw attention to this serious complication.