Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

Catherine S. Grasso,Yujie Tang,Nathalene Truffaux,Noah Berlow,Lining Liu,Marie Anne Debily,Michael J. Quist,Lara E. Davis,Elaine C. Huang,Pamelyn J. Woo,Anitha Ponnuswami,S. Chen,Tessa Johung,Wenchao Sun,Mari Kogiso,Yuchen Du,Lin Qi,Yulun Huang,Marianne Hütt-Cabezas,Katherine E. Warren,Ludivine Le Dret,Paul S. Meltzer,Hua Mao,Martha Quezado,Dannis G. van Vuurden,Jinu Abraham,Maryam Fouladi,Matthew N. Svalina,Nicholas J. Wang,Cynthia Hawkins,Javad Nazarian,Marta M. Alonso,Eric Raabe,Esther Hulleman,Paul T. Spellman,Xiao-Nan Li,Charles. Keller,Ranadip Pal,Jacques Grill,Michelle Monje

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

2015

The study describes the use of integrative approaches to search for candidate therapeutic targets for DIPG, and the identification of an HDAC inhibitor as a potential treatment strategy

Keywords:

CNS cancer
Glioma
HDAC inhibitor
Drug synergism
Brain Stem Neoplasm
Pathology
Medicine
Neuroscience
treatment strategy
Immunology

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