Neuroexcitatory Effect after Administration of Usual Dose of Epidural Morphine -A case report-

The epidural administration of opioid has been identified as a method for postoperative analgesia. However, complications such as nausea, vomiting, and respiratory depression remain major problems of an epidural administration of morphine. We experienced one case of neuroexcitation with an epidural administration of 1 mg of morphine following a total hysterectomy. The patient exhibited neuroexcitatory symptoms like myoclonus, spasm, and tingling sensations 3 hours after receiving 1 mg morphine epidurally. The symptoms resolved after stopping the morphine infusion.