Fgd5 is a Rac1-specific Rho GEF that is selectively inhibited by aurintricarboxylic acid

Sally Park,Yitian Guo,Judeah Negre,Jordane Preto,Cameron C. Smithers,Abul K. Azad,Michael Overduin,Allan G. Murray,Gary Eitzen

Fgd5 is a Rac1-specific Rho GEF that is selectively inhibited by aurintricarboxylic acid

2019

Sally Park
Yitian Guo
Judeah Negre
Jordane Preto
Cameron C. Smithers
Abul K. Azad
Michael Overduin
Allan G. Murray
Gary Eitzen

ABSTRACTRho proteins are signalling molecules that control cellular dynamics, movement and morphological changes. They are activated by Rho guanine-nucleotide exchange factors (Rho GEFs) that trans...

Keywords:

RAC1
Biology
Aurintricarboxylic acid
Cell biology
Surface plasmon resonance
signalling molecules
Guanine nucleotide exchange factor
cellular dynamics

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