Synthesis and biological activity of novel thiazolidinediones

Chebiyyam Prabhakar,G. Madhusudhan,K. Sahadev,Ch. Maheedhara Reddy,Mamillapalli Ramabhadra Sarma,G. Om Reddy,Ranjan Chakrabarti,C Seshagiri Rao,T.Dileep Kumar,Ramanujam Rajagopalan

Synthesis and biological activity of novel thiazolidinediones

1998

Chebiyyam Prabhakar
G. Madhusudhan
K. Sahadev
Ch. Maheedhara Reddy
Mamillapalli Ramabhadra Sarma
G. Om Reddy
Ranjan Chakrabarti
C Seshagiri Rao
T.Dileep Kumar
Ramanujam Rajagopalan

Novel compounds having a dual pharmacophore were synthesised and evaluated for their insulin sensitiser and anti-inflammatory properties in different animal models.

Keywords:

Chemical synthesis
Insulin
Animal model
Thiazolidinedione
Organic chemistry
Anti-inflammatory
Pharmacophore
Biological activity
Biochemistry
Chemistry
thiophene derivatives

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