Pure Transitional Cell Carcinoma of the Ovary: A Recently Recognized Rare Subtype of Ovarian Epithelial Cancer

Transitional cell carcinoma (TCC) of the ovary is a nomenclature given by Austin and Norris to a group of malignant Brenner tumors having a benign component. It is to be noted that transitional cells tumors of the ovary are not equivalent to Brenner tumor. Microscopically, Brenner tumors consist of solid and cystic nests of epithelial cells resembling transitional epithelium (urothelium), and not transitional cell epithelium in actual, surrounded by an abundant stromal component of dense, fibroblastic nature. Most authors currently favor for Brenner tumor, an origin from surface ovarian epithelium or the cysts derived from them, through a process of metaplasia. This subtype of ovarian tumor has a favorable response to chemotherapy than other ovarian surface epithelial cancers; therefore, it warrants early recognition. We hereby present a rare case report of isolated TCC of ovary.