Palladium-catalyzed asymmetric allylic alkylation of 3-aryloxindoles with allylidene dipivalate: a useful enol pivalate product.

Asymmetric allylic alkylation (AAA)[1] is a powerful and versatile method for the catalytic, asymmetric construction of quaternary stereocenters.[2] In the Mo- and Pd-AAA in particular, a broad range of functionalized electrophiles has been utilized, enabling the rapid synthesis of complex molecules in an atom- and step-economical manner.[3,4] Geminal dicarboxylates (e.g., allylidene dicarboxylates) constitute an under-explored set of electrophiles in this area.[5]