A Tri-Nucleotide Pattern in a 3' Utr Segment Affects the Activity of a Human Glucocorticoid Receptor Isoform.

ABSTRACTWe previously identified a truncated human glucocorticoid receptor (hGR) isoform of 118 amino acids, hGR-S1(-349A), that despite lacking the major functional domains, was more hyperactive after glucocorticoid treatment than the full-length receptor. Furthermore, its 3’ untranslated region (U