RESISTENSI CANDIDA ALBICANSDAN CANDIDA NON ALBICANS TERHADAP FLUKONAZOLStudi pada Isolat Rongga Mulut Penderita Infeksi HumanImmunodeficiency Virus di RSUP Dr. Sardjito

Oropharyngeal candidiasis is one of the most common opportunistic infection in HIV infection. Oropharyngel candidiasis due to azol-resistance Candida species has emerged to be one of the major problems in HIV patients. Candida albicans dan Candida non albicans have some difference in azolresistance mechanisms. The objective of the study was to compare the fluconazol-resistancy between Candida albicans dan Candida non albicans strains from oropharyngeal isolate of HIV infected patients in Sardjito Hospital. This observational study was conducted in cross sectional design. Oral rinse sample was taken from oropharyngeal of HIV infected patients. Samples were inoculated in CHROM Candida agar for species determination and subcultured in saboroud dextrose agar for fluconazole resistancy test. Candida colonization was detected in 54 (79%) patients. The Candida isolates: C.albicans 30 (40%), C. dubliniensis 15 (20%), C.dubliniensis 15 ( 20 %)