Transcriptional Regulation of Tlr11 Gene Expression in

expressiononepithelialcellsisregulated by the transcription factors that are presumably dis-tinct from transcription factors that regulate the expression ofTLRsininnateimmunecellssuchasmacrophagesandDCs.Ourresults imply that the distinctive transcription regulatorymachinery for TLRs on epithelium may represent a promisingnewavenueforthedevelopmentofepithelia-specifictherapeu-tic interventions.