Specific features of adaptation of rats to chronic cold treatment

Permanent exposure of rats to four-week cold treatment at +4oC for 24 h/day resulted in increased weights of the brown adipose tissue, adrenals, and spleen and had no effect on the levels of cortisol and corticosterone in the blood serum. Similar data were observed after exposure of rats to intermittent four-week cold treatment at +4oC for 8 h/day. After short-term exposure of rats to intermittent cold treatment at +4oC for 1.5 h/day, all indices studied were similar to those observed in intact animals.