Precocious puberty as initial presentation in mediastinal tumour

Numerous disorders can cause precocious puberty in children, and germ cell tumours (GCT) are one of the rare causes. We report two cases of mediastinal malignant GCTs who presented with precocious puberty. Both patients had bulky and advanced disease, were aggressively treated with neo-adjuvant chemotherapy and surgery, and are surviving and free of disease.