Bisbenzylisoquinoline alkaloids of lotus (Nelumbo nucifera Gaertn.) seed embryo inhibit lipopolysaccharide-induced macrophage activation via suppression of Ca2+-CaM/CaMKII pathway

ABSTRACTMacrophage hyperactivation is associated with various inflammatory diseases. In this study, the effects of nine bisbenzylisoquinoline alkaloids on NO production by LPS-activated RAW264.7 ma...