Abstract 285: Short- and Long-term Treatment of Pyridoxamine, an Inhibitor of Advanced Glycation End Products, Attenuates Platelet-neutrophil Interactions and Vascular Occlusion in Sickle Cell Disease

Jing Li,Si-Yeon Jeong,Bei Xiong,Alan Tseng,Andrew B. Mahon,Steven Isaacman,Jaehyung Cho

Abstract 285: Short- and Long-term Treatment of Pyridoxamine, an Inhibitor of Advanced Glycation End Products, Attenuates Platelet-neutrophil Interactions and Vascular Occlusion in Sickle Cell Disease

2019

Jing Li
Si-Yeon Jeong
Bei Xiong
Alan Tseng
Andrew B. Mahon
Steven Isaacman
Jaehyung Cho

Sickle cell disease (SCD) is an inherited blood disorder, leading to sickling and hemolysis of red blood cells, activation of intravascular cells, and chronic inflammation. Recurrent vaso-occlusion...

Keywords:

Hemolysis
Vascular disease
Pharmacology
Platelet
Inflammation
Cell
Medicine
Vascular occlusion
Pyridoxamine
Glycation

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