Synthesis of new 2 H -benzimidazole 1,3-dioxide derivatives analogous to separase inhibitor (Sepin-1)

New biologically active 2H-benzimidazole 1,3-dioxide derivatives, analogs of Sepin-1, have been synthesized starting from benzofuroxan. Electrophilic substitution of hydrogen in the 2H-benzimidazole ring occurs at different positions, depending on the electrophile nature.