Anatomical change during radiotherapy for head and neck cancer, and its effect on delivered dose to the spinal cord

Abstract Background and purpose The impact of weight loss and anatomical change during head and neck (HN C1LND 12.9 mm; C1SSA 12.1 cm 2 ; TNLND 5.3 mm; TNSSA 11.2 cm 2 , but no relationship between weight loss or anatomical change and ΔSCD 2% was observed (all r 2 Conclusions Differences between delivered and planned spinal cord D 2% are small in patients treated with daily IG. Even patients experiencing substantial weight loss or anatomical change during treatment do not require adaptive replanning for spinal cord safety.