A pilot study to evaluate the effect of a novel calcium and vitamin D-containing oral bolus on serum calcium levels in Holstein dairy cows following parturition

Abstract The initiation of lactation challenges the ability of the modern lactating cow to maintain calcium homeostasis, and typically results in a drop in blood calcium levels; leading to mobilization of calcium reserves from skeletal stores. As such, the recommendation to provide supplemental calcium at parturition to older cows has become an industry-standard practice. Mature cows were treated at calving and 12 hours later with either the novel calcium bolus (NB), or a commercially available calcium bolus (CB). Blood was collected from animals at 0, 1, 6, 12, 13, and 24 hours following calving, and the resulting serum samples were analyzed. Overall, there was no statistical difference between the NB and CB groups for blood calcium levels within the first 24 hours following parturition (P = 0.50). Cows in both groups experienced a significant increase in serum calcium by 1 hour after parturition; however, this increase was not sustained through subsequent sampling times. This pilot study demonstrates that both boluses have a similar effect in the elevation of blood calcium.