Poster Session：PS 1098 ; Gastroenterology (Gastrointestinal Tract) : A Rare Case of Hepatoid Carcinoma Detected on Colonoscopy for Colon Cancer Work Up

Background: We described a rare case of an alpha-fetoprotein-producing carcinoma originated in the Ascending colon of a 76-year old man. Methods: The patient was reported an abdominal mass and tenderness on RLQ area. He was diagnosed with colon cancer in CT. But the result of colonoscopy performed at other hospital was acute colitis. On our hospital`s examination, partial obstruction was noticed on the proximal A -colon and hepatic fi exure and found a tumor of the ascending colon and 1. 7cm sized osteolytic metastatic lesion with cortical destruction in L4 body. The serum alpha-fetoprotein level was 12. 42 ng/ml. The patient was performed endoscopic biopsy via colonoscopy examination. Results: Histologically, the colon cancer was hapatoid carcinoma. It`s composed of large polygonal tumor cells with sheet formation and distinct cell borders. Unfortunately, the patient had been suffer from massive hematochezia and died due to disseminated intravascular coagulation in a week. Conclusion: We reported a rare case of hepatoid carcinoma was generally associated with a poor prognosis because of the high angioinvasiveness.