Microwave-Assisted Direct Synthesis of Nitriles from Aromatic Aldehydes under Solvent-Free Condition

A simple and convenient one - pot protocol for preparing nitriles by treating different aromatic aldehydes with hydroxylamine hydrochloride in the presence of Na 2 CO 3 - a simple, mild, and inexpensive catalyst, without any s olvent under microwave irradiation is reported. The significant features of the present protocol are simplicity, high yields, short reaction time, involvement of non - aqueous work - up procedure, environmentally benign nature, using of microwave reactor and n o chromatographic purification.