Meme kanserinde protein ekspresyon değişimleri ve önemi Protein expression changes in breast cancer and their importance

Studies about nucleic acids have increased after the publication of DNA’s three dimensional structure by Watson and Crick. Nucleic acids are the heritable molecules which contain codes for proteins. Proteins are the most important elements in molecular world because they are the basic structural and functional components of a living organism. Clarifying the celluler events that involve proteins are important in many areas for example diagnosis and treatment determination of diseases or development of new drugs. Proteome that comes from a combination of the terms protein and genome, is one of the important field in these days. The studies in this area have accel erated and gained a different place especially with after the completion of human genome project. In synthesis of a protein just only genetic information is not enough. At the same time the change or changes of a protein after the synthesis, the final version and transporting to final localization of it also important. Because having defects in mailing cells of breast cancer, the first targets of treatment must be proteins. In this way the studies on proteins are important to determine prognostic and diagnostic disease markers and also significant for identifying new treatment strategies. OZET