Computer method for the assessment of epithelial metaplasia in human bronchial mucous membrane

: Using Bio Vision computer program, the successive stages of metaplastic changes development were traced in the pseudostratified columnar ciliated epithelium of bronchial mucous membrane obtained from 65 patients with bronchial asthma of various degrees of severity. Biopsy material analysis demonstrated the changes of cell nuclear and cytoplasmic density, as well as of basement membrane.