Synthesis of 4-allyl-4-arylaminopiperidines and their transformations to spiro[tetrahydroquinoline-2,4′-piperidines]
1989
It was established that the yields of a 4-allyl-4-aryl-aminopiperidines in the reaction of 4-aryliminopiperidines with allylmagnesium bromide increase significantly if the reaction is carried out in the presence of a crown ether. A number of previously unknown spiro[tetrahydroquinoline-2,4′-piperidines] were obtained in the cyclization of 4-allyl-4-arylaminopiperidines in the presence of sulfuric acid.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
4
References
2
Citations
NaN
KQI