Cyclethrin induced Histopathological and Histochemical changes in the liver of the catfish, Clarias batrachus

The investigation was aimed to assess effect of the pyrethroid – Insecticide used in paddy fields flows in nearby water resources on the histology and histochemistry to 1/10LC50 for 4 and 7 days under ecological conditions of PH, temperature, acidity and hardness of water. The results showed that the histopathological changes induced in the liver were often represented by cytoplasmic vacuolization of the liver cell (Hepatocytes), blood vessel congestion, inflammatory, leucocytic infiltration, necrosis and lipid infiltration. The histo chemical level reveals reduction in glycogen content and total protein content of the hepatocytes with increasing activity of enzymes related to improving filtration mechanism in body.