CEVİZ (JUGLANS REGIA L.)'İN ANTİMİKROBİYAL AKTİVİTESİ ANTIMICROBIAL ACTIVITY OF WALNUT (JUGLANS REGIA L.)

SUMMARY In this study, aqueous and methanol extracts of the walnut (Juglans regia L.) green husks and leaves were investigated for their in vitro antimicrobial activities. Th e green husks and leaves were collected from Erzincan (Kemah) region. Th e antimicrobial activity of extracts against some clinical isolates Candida spp (Candida albicans, Candida glabrata, Candida tropicalis, Candida parapsilosis, Candida krusei, Candida kefyr, C andida guilliermondii, Geotrichum candidum); Gram negative bacteria (Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes) and Gram positive bacteria (Staphylococcus aureus, Staphylococcus epidermidis) were evaluated based on inhibition zone using the disc-diff usion assay, minimal inhibition concentration (MIC) values. As a result of this study, water and methanol extracts of walnut green husks and leaves demonstrated antimicrobial activity against S.aureus, S.epidermidis, P.aeruginosa, C. albicans, C. glabrata, C.tropicalis and C. kefyr isolates.