Primary adenosquamous carcinoma of the stomach

BACKGROUND: Primary adenosquamous carcinoma of the stomach is a rare tumour, the incidence of which does not exceed 1% of gastric tumours. This tumour shows two different cell components: one squamous and the other adenomatous. MATERIAL AND METHODS: The authors report a case of a primary adenosquamous carcinoma of the stomach in a 55-year-old Caucasian (white) man, whose pathology and immunohistochemistry show the presence of both types of cells: adenomatous and squamous. CONCLUSION: The authors show an interesting and rare case of adenosquamous tumour, discuss its pathogenesis, diagnosis, clinics and pathologic features.