GW25-e2319 Effects and mechanisms of Angiotensin (1-7) on expression of inflammatory cytokines in macrophage foam cells

To explore if Angiotensin (1-7) can modulate the expression of inflammation cytokines in macrophage foam cells and the involvement of TLR4/NF-κB signaling pathway in this process. THP-1 cells were induced into macrophages by 130ng/mL phorbol myristate acetate (PMA) for 48h.The THP-1-derived