Nano-fiber tubular scaffold with multi-stage porous structure
2010
The invention relates to a tissue engineering tubular scaffold with a multi-stage porous structure. The scaffold comprises at least one channel which is axially arranged, the area of the cross section of the channel is 300 mu m2-300 mm2, the non-channel part of the scaffold has micropores which are interconnected, the volume range of the micropores is 1 mu m3-5000 mu m3, the pore diameter distribution curve of the micropores is serrated, and the microporous wall of the scaffold is a nano-fiber three-dimensional network. Simultaneously, drugs with the function of changing physiological actionsof cells and tissues are contained in the scaffold, the functional drugs are released according to a certain rule to the environment located by the scaffold during the application process, and the types, the loading quantities and the release rate of the drugs can be set according to the actual needs. The tissue engineering scaffold with a fine topological structure and the physiological functionhas broad prospects.
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