18F-Choline, 68Ga-PSMA-11 and 18F-FDG PET/CT in Treatment Response Evaluation: Prostate Cancer

PET/CT imaging is a useful diagnostic procedure for investigating prostate cancer (PCa). Over the last decade, PET/CT with 11C-Choline or 18F-Choline proved its role for investigating PCa and proved to be a better diagnostic tool for restaging PCa patients presenting biochemical recurrence (BCR), as compared with radiological imaging. However, over the last years, new probes able to provide better performances when compared with choline PET/CT were developed. PSMA is a molecular probe targeting the prostate-specific membrane antigen (PSMA). In general, PSMA PET might be considered as a valuable tool to assess the response to treatment after radioligand therapy. In this chapter, we present several case scenarios in response assessment of prostate cancer.