EPA-0598 – Psychological risk factors in essential hypertension:new insights to gender variations

Introduction Modern psychosomatic research has found multiple evidence for an impact of psychosocial factors on the development of arterial hypertension. Aims To evaluate the burden of these factors among the two sexes. Methods A sample of 198 hypertensive patients (89 men – 108 women, mean age 52,9 years, SD = 11,81 ranged 26–78) participated to the present study. The questionnaires included: a) questionnaire recording social-demographic characteristics and clinical features, b)The Short Form 36 (SF-36) General Health Survey questionnaire, c) the Beck Depression Inventory –II, d) Eysenck Personality Questionnaire and e) The Cardiac Anxiety Questionnaire (CAQ-greek version). SPSS for Windows 14.0 and STATA 10 were used for statistical analysis. Results Age was not differ significantly among the two sexes (t = −1.638, p =.028). Models of stepwise approach logistic regression, examining the associations between gender and psychological issues, were performed. Model 1 was adjusted for age, socio-demographic variables and clinical parametres. Quality of life, depression, personality traits, and cardiac anxiety scores were introduced in step model 2. In model 3, after controlling for age, socio-demographic variables and clinical features female hypertensive participants had a higher risk of somatization (OR=1.46, 95% CI=1.02–1.29), paranoid ideation (OR=1.23, 95% CI=1.04 –1.46) and psychotisism (OR=1.37, 95% CI=1.14–2.45). Conclusions Findings support the hypothesis that hypertensive women shows a serious psychological dysfunctional behaviour, which can be attributed to their gender. Since this relation was not explained by relevant confounders there is a need for create preventive methods or treatment programmes in order to minimaze these effects