miR-145 functions as tumor suppressor and targets two oncogenes, ANGPT2 and NEDD9, in renal cell carcinoma.

Ruijing Lu,Ziliang Ji,Xiaoqing Li,Qingna Zhai,Chunjuan Zhao,Zhimao Jiang,Shiqiang Zhang,Liping Nie,Zhendong Yu

miR-145 functions as tumor suppressor and targets two oncogenes, ANGPT2 and NEDD9, in renal cell carcinoma.

2014

Ruijing Lu
Ziliang Ji
Xiaoqing Li
Qingna Zhai
Chunjuan Zhao
Zhimao Jiang
Shiqiang Zhang
Liping Nie
Zhendong Yu

Purpose Abnormal expression of miRNAs is closely related to a variety of human cancers. The purpose of this study is to identify new tumor suppressor miRNA and elucidate its physiological function and mechanism in renal cell carcinoma (RCC).

Keywords:

Immunology
microRNA
Pathology
NEDD9
Renal cell carcinoma
Biology
physiological function
abnormal expression
Hematology
Suppressor
Internal medicine

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