Abstract 38: Intensive Monitoring of Cardiac Function and Extravascular Lung Water Predicts Outcome of Tako-tsubo Cardiomyopathy after Subarachnoid Hemorrhage

Takotsubo cardiomyopathy (TCM) is a life-threatening systemic consequence early after subarachnoid hemorrhage (SAH), but precise hemodynamics and related outcome are not well-understood. We aimed to investigate the TCM-induced cardiac function by transpulmonary thermodilution and its impact on clinical outcome of SAH. Forty-six consecutive SAH patients who developed TCM and treated surgically or endovascularly were analyzed retrospectively. Patients were divided into two groups of LVEF <40% (TCM with LV dysfunction) and LVEF ≥40% (TCM without LV dysfunction). Cardiac function index (CFI) and extravascular lung water index (ELWI) were monitored by transpulmonary thermodilution. Transpulmonary thermodilution-derived CFI was correlated significantly with echocardiographic left ventricular ejection fraction (LVEF) (r = 0.82, P <0.0001). The CFI between day 0 to day 7 was significantly lower in patients with LV dysfunction (LVEF <40%) than in patients with LVEF ≥40% (P <0.05). CFI had a better ability than car...