Эпидемиологические риски развития ретинобластомы в промышленном регионе

2015 
Objective. Incidence rates of retinoblastoma in the Kemerovo region for the period from 1984 to 2013 as a whole, as well as a separate time periods I (1984-1993), II (1994-2003), III (2003-2013). Methods. To characterize the incidence, a method of direct standardization was used. To analyze the statistical relationship, the Kendall correlation coefficient was used. Results. The incidence rate in the region increased from 4,02 in the I period to 8,50 per 100 thousand newborn in the III period. The frequency of such cases in the last decade amounted to 1 : 11999 newborns. There were areas identified areas with high incidence rates, and areas with no reported cases of retinoblastoma during the entire period of the study. The majority of children were represented by the urban population to 72,4 %, rural to 27,6 %. The incidence rate of retinoblastoma in cities and regions with high anthropogenic load accounts for 81 % of all cases. Statistically was found a direct correlation between anthropogenic indicators in the districts and standardized incidence of retinoblastoma. Conclusions. The incidence rate of retinoblastoma in the areas of the region has a wide range. Among the urban population the figure is 2,5 times higher than in rural areas. There is a higher incidence in the cities and industrial areas with developed industry.
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