Study of synthesis of isooctyl para-dimethylaminobenzoate as sun-screening agent

A new technology of synthesizing isooctyl para-dimethylaminobenzoate and the factors affecting the yield of product were studied.With p-nitrobenzoic acid and isooctanol as starting materials,isooctyl p-dimethylaminobenzoate was prepared in three steps:esterification,nitryl hydrogenation and N-alkylation.N-alkylation reaction was studied mainly,and the optimum reaction conditions are as follows:reaction temperature 90 ℃～100 ℃;reaction time 15 h;content of catalyst 10 %;molar ratio of para-aminobenzoate to formaldehyde 10∶22;the general yield of prduct is 847 %,furthermore,it is needless to use virulent sulfuric acid dimethyl ester.