Characterization of plasma protein binding in two mouse models of humanized liver, PXB mouse and humanized TK-NOG mouse

Maki Miyamoto,Yohei Kosugi,Shinji Iwasaki,Ikumi Chisaki,Sayaka Nakagawa,Nobuyuki Amano,Hideki Hirabayashi

Characterization of plasma protein binding in two mouse models of humanized liver, PXB mouse and humanized TK-NOG mouse

2020

Maki Miyamoto
Yohei Kosugi
Shinji Iwasaki
Ikumi Chisaki
Sayaka Nakagawa
Nobuyuki Amano
Hideki Hirabayashi

The unbound fractions in plasma (f up) in two mouse models of humanized liver mice, PXB and humanized TK-NOG mice, were compared with human f up values using equilibrium dialysis method. A good rel...

Keywords:

Chemistry
Molecular biology
Plasma protein binding

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