Gallium-68 Complexes Conjugated to Pittsburgh Compound B: Radiolabeling and Biological Evaluation

Damien Cressier,Martine Dhilly,Thang T. Cao Pham,Fabien Fillesoye,Fabienne Gourand,Auriane Maïza,André F. Martins,Jean-François Morfin,Carlos F. G. C. Geraldes,Éva Tóth,Louisa Barré

Gallium-68 Complexes Conjugated to Pittsburgh Compound B: Radiolabeling and Biological Evaluation

2016

Damien Cressier
Martine Dhilly
Thang T. Cao Pham
Fabien Fillesoye
Fabienne Gourand
Auriane Maïza
André F. Martins
Jean-François Morfin
Carlos F. G. C. Geraldes
Éva Tóth
Louisa Barré

Purpose The aim of this work is to develop an efficient and fully automated radiosynthesis of three derivatives of the Pittsburgh compound B labeled with gallium-68 for the detection of amyloid plaques.

Keywords:

Medicine
Combinatorial chemistry
Nuclear medicine
Conjugated system
Radiosynthesis
Gallium
Pittsburgh compound B
biological evaluation
automated radiosynthesis
fully automated

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