Uterine rupture at term pregnancy with the use of intracervical prostaglandin E2, gel for induction of labor

Prostaglandin E 2 is a powerful oxytocic agent that reliably initiates labor, even in the presence of an unripe cervix. The low incidence of fetomaternal complication contributes to its universal use. We report a rare case of uterine rupture after intracervical application of prostaglandin E 2 gel. Thus far no prostaglandin compound or method of administration seems to be exempt from such a complication.