Fine tuning of calcium on membrane excitation of baroreceptor neurons in rats

electrophysiologically remodels the membraneexcitation in physiological or disease condition. Membrane excitabilityis a common feature in all excitable tissues including baroreceptorneurons (BRNs) to achieve their normal function. The evidences showthat all major ion channels contribute to stabilize the membrane inBRNs.PreviousdatashowthattheresponsesofBRNstoelectronicstim-ulus are quite different upon the afferent types.Intriguing observationsfrom the cardiovascular literature have provided quantitative evidencethat myelinated and unmyelinated cardiovascular afferents evoke notonlydifferentfrequency-dependentreflexresponsesbutalsopotential-ly and distinctly different sensory information processing mechanisms[3]. Whereas the frequency-dependent spike often leads to increasedinflux of Ca