Chapter 26 – Transplantation of Myogenic Cells in Duchenne Muscular Dystrophy Patients: Clinical Findings

Duchenne muscular dystrophy is a genetic degenerative myopathy that causes progressive and irreversible loss of skeletal muscles. The transplantation of myogenic cells is an experimental strategy for the potential treatment of this disease. Although the repertoire of myogenic cells appears to have expanded in recent years, myoblasts are the only cells that have demonstrated to significantly engraft in clinical trials. In this chapter, we present the most relevant of the clinical experience made so far, in which our laboratory has had a greater involvement in the development of better transplantation protocols.