Original Paper Microscopic findings in liver steatosis in HIV- infected children and dead with AIDS

The present histological study followed the presence of liver steatosis in HIV-infected children subsequently dead with AIDS. At autopsy, liver specimens have been sampled from 22 subjects in B and respectively C clinical and immunological stages. The liver specimens have been processed for paraffin embedding, then cut with a microtom into 3-5 micrometer-thick sections, which were stained with haematoxylin-eosin and thricrome Goldner- Szekelly. The presence of liver steatosis was identified in 16 cases (72,8%), in the other 6 cases no steatotic changes being identified. In these 16 cases with presence of liver steatosis, steatosis was graded as follows: mild steatosis in 6 cases (37,5%), moderate steatosis in 4 cases (25%) and severe and massive steatosis in 6 cases (37,5%).The microscopically aspect of liver steatosis, was the most frequently described, as macrovesicular in 8 cases, in 4 cases there were microvesicular changes, and the other 4 cases presented with a mixed aspect, macrovesicular and microvesicular.