Hepatic Angiomyolipoma: a report of 2 cases and review of literature

Objective:To investigate the clinicopathologic features and differential diagnosis of hepatic angiomyolipoma.Methods:2 cases of hepatic angiomyolipoma were studied clinicopathologically and immunohistochemically combined with literature.Results:Clinically the victims had discomfort on right upper abdomen and occupying lesions on imaging. Immunohistochemically, the tumor cells were positive for HMB45, CD117, focally positive for SMA and negative for cytokeratine and AFP.Conclusions:Hepatic angiomyolipoma is a rare mesenchymal neoplasm and its histogenesis may derive from a perivascular epithelioid cell capable of coexpressing myoid and melancytic markers. Its definite diagnosis has to rely on histopathology and immunohistochemistry.