Emerging roles in prolactin-mediated BRCA1 function
2016
In a recent issue of Cancer Letters , Chen et al . reported that prolactin may inhibit a major tumor-suppressive function of BRCA1 by interfering with the BRCA1-related cell cycle inhibitor, p21 (1). These findings are interesting and will open up a controversial discussion on the role of prolactin in tumorigenesis.
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